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ADH increases the permeability of the distal convoluted tubules and collecting ducts by


A) incorporating aquaporin-3 channels into the apical membrane.
B) increasing the number of sodium transpot proteins in the membranes.
C) incorporating aquaporin-2 channels into the apical membrane.
D) decreasing the number of aquaporin-4 channels in the apical membrane.

E) A) and B)
F) A) and C)

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The filtrate that drips from the renal papillae into the calyces


A) has a higher concentration of waste products (urea) than the original filtrate.
B) may have lost up to 99% of its original volume.
C) is called urine.
D) has a higher concentration of waste products (urea) than the original filtrate, may have lost up to 99% of its original waste, and is called urine.
E) None of these choices is correct.

F) B) and D)
G) All of the above

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Blood loss that occurs during surgery will stimulate cells in the


A) efferent arteriole.
B) wall of the right atrium.
C) proprioceptors.
D) juxtaglomerular apparatus.
E) None of these choices is correct.

F) A) and E)
G) A) and D)

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The mechanism for concentration of urine is called the _____________ mechanism.


A) countercurrent
B) filtration
C) secretion
D) reabsorption
E) concentration

F) B) and E)
G) D) and E)

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The renal corpuscle consists of


A) the renal pelvis and the renal tubules.
B) the glomerulus and Bowman's capsule.
C) Bowman's capsule and the renal pelvis.
D) the proximal convoluted tubule and the glomerulus.
E) afferent and efferent arteriole.

F) B) and D)
G) A) and E)

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Which of the following statements is true?


A) Only sodium diffuses from the descending limb.
B) Solutes are actively transported from the ascending limb.
C) Na+ and Cl- ions are actively transported into the vasa recta.
D) The osmolality of the descending limb decreases as filtrate moves through.
E) Water moves by osmosis out of the ascending loop.

F) A) and B)
G) C) and D)

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At the rate of 125 ml of filtrate/minute, estimate the amount of filtrate formed in 24 hours.


A) 45 liters
B) 90 liters
C) 125 liters
D) 180 liters
E) 200 liters

F) A) and E)
G) All of the above

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Autoregulation in the kidney involves changes in the degree of


A) constriction of afferent arterioles.
B) sympathetic stimulation.
C) aldosterone secretion.
D) ADH secretion.
E) None of these choices is correct.

F) A) and D)
G) A) and C)

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Glucose is usually completely reabsorbed from the filtrate by the time the filtrate has reached the


A) tip of the loop of Henle.
B) end of the collecting duct.
C) end of the distal convoluted tubule.
D) end of the proximal convoluted tubule.
E) beginning of the proximal convoluted tubule.

F) A) and B)
G) A) and C)

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Atrial natriuretic hormone


A) promotes the secretion of ADH.
B) is secreted by the posterior pituitary.
C) causes the formation of concentrated urine.
D) is secreted when atrial blood pressure increases.
E) is secreted when atrial blood pressure decreases.

F) A) and C)
G) All of the above

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Which of the following are most likely to be actively secreted into the distal convoluted tubule?


A) potassium ions.
B) chloride ions.
C) bicarbonate.
D) amino acids.
E) sodium.

F) C) and D)
G) A) and E)

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Which of the following structures is a capillary?


A) glomerulus
B) loop of Henle
C) collecting duct
D) Bowman's capsule
E) proximal convoluted tubule

F) A) and E)
G) A) and D)

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A substance that is useful for determining the plasma clearance rate of the kidney is


A) ADH.
B) glucose.
C) inulin.
D) protein.
E) ammonia.

F) D) and E)
G) A) and E)

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Diabetes insipidus is the result of decreased


A) ADH production.
B) insulin production.
C) aldosterone production.
D) angiotensin II production.
E) glucagon production.

F) A) and B)
G) C) and E)

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The vasa recta


A) supplies blood to the glomerulus.
B) alters the cortical solute gradient.
C) collects excess water and solutes from the medullary interstitial fluid.
D) collects water and solutes reabsorbed from the proximal convoluted tubule.
E) surrounds the collecting duct.

F) All of the above
G) B) and D)

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What are the arteries which diverge from the interlobar arteries near the base of the renal pyramid?


A) Arcuate
B) Pertibular
C) Segmental
D) Renal
E) Interlobular

F) A) and E)
G) B) and D)

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Which of the following would help maintain the medullary concentration gradient?


A) movement of urea from the distal convoluted tubule to the proximal convoluted tubule
B) urea movement from the collecting duct to medullary interstitial fluid
C) movement of water from the ascending limb into the medullary interstitial fluid
D) active transport of sodium and chloride from the medullary interstitial fluid into the collecting duct
E) urea movement into the collecting duct

F) A) and B)
G) A) and C)

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Formation of filtrate depends on a


A) pressure gradient.
B) concentration gradient.
C) volume gradient.
D) temperature gradient.
E) osmotic gradient.

F) D) and E)
G) B) and E)

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The tip of each renal pyramid is called


A) a nephron.
B) a renal papilla.
C) a renal column.
D) a medullary ray.
E) the apex.

F) C) and D)
G) B) and D)

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Hydrogen ions are secreted into the filtrate by both the


A) proximal and distal convoluted tubules.
B) collecting duct and Bowman's capsule.
C) loop of Henle and the distal convoluted tubule.
D) proximal convoluted tubule and the loop of Henle.
E) loop of Henle only.

F) A) and D)
G) A) and C)

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