Question 1

What role does the amino acid itself play in the accurate placement of the charged tRNA at the codon?

Accepted Answer

None. Experiments have demonstrated that...

Question 2

Describe the subunits of E. coli ribosomes.

Accepted Answer

E. coli ribosomes contain a large (50S) ...

Question 3

What biomolecule delivers the aminoacyl-tRNA to the "A site" of the E. coli ribosome?

Accepted Answer

A)   initiation factor-1
B)   initiation factor-3
C)   elongation factor-G
D)   elongation factor-Ts
E)   elongation factor-TuF) B) and E)
G) A) and B)

Question 4

How much energy is used to attach the amino acid to the tRNA?

Accepted Answer

The equiva...

Question 5

In E. coli, the signal sequence that properly aligns the initiation codon in the P site is called the ______________________ sequence.

Accepted Answer

The answer of In E. coli, the signal sequence that...

Question 6

What is another name for an amino acid ester of a tRNA?

Accepted Answer

A)   linked tRNA
B)   loaded tRNA
C)   esterified tRNA
D)   charged tRNA
E)   filled tRNAF) C) and E)
G) None of the above

Question 7

What hypothesis explains why some tRNA molecules can bind to more than one codon?

Accepted Answer

A)   jiggle hypothesis
B)   shimmy hypothesis
C)   teeter hypothesis
D)   totter hypothesis
E)   wobble hypothesisF) A) and B)
G) C) and E)

Question 8

The activation of a tRNA involves the formation of a(n) __________________ intermediate.

Accepted Answer

The answer of The activation of a tRNA involves the...

Question 9

Explain why some bases in some RNAs cannot be involved in base pairs.

Accepted Answer

Some RNA contains unusual base...

Question 10

What is the function of yeast alanyl-tRNA?

Accepted Answer

It carries the amino acid alanine, which is incorporated into a polypeptide chain.

Question 11

The first amino acid in bacterial proteins is __________________

Accepted Answer

N-formylme...

Question 12

Class ____________ aminoacyl-tRNA synthetases acylate the 2′ hydroxyl group of the terminal adenosine of tRNA.

Accepted Answer

The answer of Class ____________ aminoacyl-tRNA synthetases acylate the 2′...

Question 13

Using structures of the base pairs, show how the presence of inosine at the 5′ position of the anticodon can recognize three different codons.

Accepted Answer

The answer of Using structures of the base pairs, show...

Question 14

Eukaryotic and bacterial translation differ primarily in the ________ step(s) .

Accepted Answer

A)   initiation
B)   elongation
C)   termination
D)   All of the answers are correct.
E)   None of the answers is correct.F) B) and E)
G) None of the above

Question 15

What are some of the features common to tRNA molecules?

Accepted Answer

A)   Each is a single chain between 73 and 93 ribonucleotides.
B)   They contain many unusual bases.
C)   About half the nucleotides in tRNA are base-paired.
D)   They usually have a pG at the 5′ terminal.
E)   All of the answers are correct.F) C) and E)
G) A) and E)

Question 16

What region of a tRNA often contains large amounts of inosine?

Accepted Answer

A)   acceptor arm
B)   D arm
C)   T Ψ\PsiΨ C arm
D)   anticodon loop
E)   extra arm F) B) and D)
G) A) and B) D

Question 17

In preparation for attachment to the tRNA, amino acids are activated by

Accepted Answer

A)   methylation.
B)   adenylation.
C)   N-acetylation.
D)   formylation.
E)   None of the answers is correct.F) A) and B)
G) A) and C) B

Question 18

Which component of the tRNA is most important for the binding specificity of the tRNA synthetase?

Accepted Answer

A)   variable loop
B)   anticodon loop
C)   TΨC loop
D)   CCA 3ʹ terminus
E)   DHU loopF) A) and B)
G) All of the above

Question 19

What is the order of the tRNA binding sites on the 70S ribosome with respect to the 5′-3′ direction of the mRNA?

Accepted Answer

A)   E P A
B)   P A E
C)   A E P
D)   E A P
E)   A P EF) A) and D)
G) None of the above

Question 20

What term refers to the polygenic nature of bacterial mRNA?

Accepted Answer

A)   polytranslated mRNA
B)   polytranscribed mRNA
C)   polycistronic mRNA
D)   polymeric mRNA
E)   None of the answers is correct.F) C) and E)
G) None of the above

Exam 30: Protein Synthesis

What role does the amino acid itself play in the accurate placement of the charged tRNA at the codon?

Correct AnswerverifiedNone. Experiments have demonstrated that...View AnswerShow Answer

Describe the subunits of E. coli ribosomes.

Correct AnswerverifiedE. coli ribosomes contain a large (50S) ...View AnswerShow Answer

What biomolecule delivers the aminoacyl-tRNA to the "A site" of the E. coli ribosome?

Correct AnswerverifiedShow Answer

How much energy is used to attach the amino acid to the tRNA?

Correct AnswerverifiedThe equiva...View AnswerShow Answer

In E. coli, the signal sequence that properly aligns the initiation codon in the P site is called the ______________________ sequence.

Correct AnswerverifiedShow Answer

What is another name for an amino acid ester of a tRNA?

Correct AnswerverifiedShow Answer

What hypothesis explains why some tRNA molecules can bind to more than one codon?

Correct AnswerverifiedShow Answer

The activation of a tRNA involves the formation of a(n) __________________ intermediate.

Correct AnswerverifiedShow Answer

Explain why some bases in some RNAs cannot be involved in base pairs.

Correct AnswerverifiedSome RNA contains unusual base...View AnswerShow Answer

What is the function of yeast alanyl-tRNA?

Correct AnswerverifiedIt carries the amino acid alanine, which is incorporated into a polypeptide chain.

The first amino acid in bacterial proteins is __________________

Correct AnswerverifiedN-formylme...View AnswerShow Answer

Class ____________ aminoacyl-tRNA synthetases acylate the 2′ hydroxyl group of the terminal adenosine of tRNA.

Correct AnswerverifiedShow Answer

Using structures of the base pairs, show how the presence of inosine at the 5′ position of the anticodon can recognize three different codons.

Correct AnswerverifiedShow Answer

Eukaryotic and bacterial translation differ primarily in the ________ step(s) .

Correct AnswerverifiedShow Answer

What are some of the features common to tRNA molecules?

Correct AnswerverifiedShow Answer

What region of a tRNA often contains large amounts of inosine?

Correct AnswerverifiedD

In preparation for attachment to the tRNA, amino acids are activated by

Correct AnswerverifiedB

Which component of the tRNA is most important for the binding specificity of the tRNA synthetase?

Correct AnswerverifiedShow Answer

What is the order of the tRNA binding sites on the 70S ribosome with respect to the 5′-3′ direction of the mRNA?

Correct AnswerverifiedShow Answer

What term refers to the polygenic nature of bacterial mRNA?

Correct AnswerverifiedShow Answer

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None. Experiments have demonstrated that...
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E. coli ribosomes contain a large (50S) ...
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The equiva...
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Some RNA contains unusual base...
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It carries the amino acid alanine, which is incorporated into a polypeptide chain.

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N-formylme...
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Correct Answer
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D

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B

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