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Which of the following is incorrect about in?ammation?


A) Fever could be bene?cial to inhibiting the pathogen.
B) In?ammation can last hours to years.
C) Basophils and mast cells release histamine.
D) Pyrogens cause vasodilation and increased capillary permeability.
E) Serotonin causes smooth muscle contraction.

F) A) and E)
G) A) and B)

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The main function of the mononuclear phagocyte system is to provide ______.


A) a connection between tissues and organs
B) surveillance cells
C) filtration of extracellular fluid
D) filtration of blood

E) A) and B)
F) All of the above

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A type of monocyte that has long, thin processes to trap pathogens is a/an ______.


A) platelet
B) dendritic cell
C) mast cell
D) eosinophil
E) macrophage

F) B) and C)
G) All of the above

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During what process are hypochlorite and hydrogen peroxide produced in order to destroy bacteria and inhibit viral replication?


A) Lysozyme production
B) Complement production
C) Interferon production
D) Inflammation
E) Phagocytosis

F) C) and D)
G) A) and D)

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The production of interferon will protect the host cell from a viral infection.

A) True
B) False

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Endotoxin is an exogenous pyrogen.

A) True
B) False

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Plasma cells ______.


A) function in cell-mediated immunity
B) produce and secrete antibodies
C) are derived from T lymphocytes
D) function in blood clotting

E) B) and C)
F) A) and D)

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Which of the following is a chemical used by phagocytes to destroy ingested foreign substances?


A) Hydrogen peroxide
B) Nitric oxide
C) Lactic acid
D) Superoxide anion
E) All of these choices are used.

F) A) and E)
G) A) and B)

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The mononuclear phagocyte system (MPS) is an intricate network throughout the body that comprises ______.


A) connective tissue fibers and phagocytic white blood cells
B) connective tissue fibers, mast cells, and basophils
C) connective tissue and monocytes
D) connective tissue and lymphocytes

E) None of the above
F) C) and D)

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Which of the following is mismatched in relation to inflammation?


A) Tumor - cancer
B) Calor - warmth
C) Rubor - redness
D) Dolor - pain

E) C) and D)
F) None of the above

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Hematopoiesis is the ______.


A) migration of white blood cells from the blood out to the tissues
B) loss of blood due to hemorrhaging
C) plugging of broken vessels to stop bleeding
D) production of only red blood cells
E) production of white blood cells, red blood cells, and platelets

F) C) and E)
G) C) and D)

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A patient visits your clinic often with recurrent respiratory infections. Based upon their medical history, it appears they have been an active smoker for over 40 years. Select the statement that most accurately re?ects how this information may reveal why the patient is highly susceptible to respiratory pathogens.


A) Smoking decreases the activity of neutrophils.
B) Smoking directly inhibits B- and T-cell action.
C) Smoking decreases the formation and effectiveness of complement proteins.
D) Smoking can paralyze the ciliary escalator.

E) C) and D)
F) None of the above

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Which of the following represents the correct order of activity in the complement cascade?


A) Membrane attack, initiation, polymerization, and amplification
B) Initiation, amplification, polymerization, and membrane attack
C) Amplification, initiation, membrane attack, and polymerization
D) Polymerization, initiation, membrane attack, and amplification
E) Initiation, membrane attack, polymerization, and amplification

F) None of the above
G) C) and D)

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Microbial antagonism is the ______.


A) suppression of the complement cascade by microbes
B) prevention of immune responses by the resident microbiota
C) inhibition of T cell binding to microbes
D) competition for nutrients, oxygen, and space between the resident microbiota and potential pathogens

E) C) and D)
F) B) and C)

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You cut your finger dicing chicken for dinner. Which of the following is not a source of chemicals that stimulate the inflammatory response that results from the injury?


A) Antibody-producing plasma cells
B) Host tissues damaged by the knife
C) Localized leukocytes
D) Bacterial cells that infect the wound

E) B) and D)
F) C) and D)

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Nonspeci?c chemical defenses include _______.


A) lysozyme
B) lactic acid and electrolytes of sweat
C) the skin's acidic pH and fatty acids
D) stomach hydrochloric acid
E) All of the choices are correct.

F) B) and D)
G) A) and C)

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The alternate complement pathway uses complement proteins C1, C2, and C4.

A) True
B) False

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The membrane attack stage of the complement cascade involves ______.


A) the cleaving of C3 to yield C3a and C3b
B) initiation of the cascade
C) a ring-shaped protein digesting holes in bacterial cell membranes and virus envelopes
D) C1q binding to surface receptors on a membrane
E) the production of inflammatory cytokines

F) A) and B)
G) A) and C)

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The leakage of vascular fluid into tissues is called ______.


A) edema
B) diapedesis
C) pus
D) chemotaxis
E) vasoactivity

F) C) and D)
G) All of the above

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What type of molecules act to draw phagocytes to foreign substances?


A) RES
B) PAMPs
C) MALTs
D) IFNs
E) BALTs

F) A) and B)
G) D) and E)

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