Question 1

Varicella vaccine may be given to patients who are:

Accepted Answer

A)  HIV positive with a CD4+ T-lymphocyte percentage less than 15%
B)  Taking corticosteroids (up to 2 mg/kg/day or less than 20 mg/day) 
C)  Pregnant
D)  ImmunocompromisedE) A) and B)
F) A) and C)

Question 2

Live attenuated influenza vaccine (FluMist)  may be administered to:

Accepted Answer

A)  All patients over six months of age
B)  Patients between ages 2 and 49 with no risk factors
C)  Patients with an upper respiratory infection (URI)  or asthma
D)  Pregnant womenE) A) and B)
F) A) and C) A

Question 3

A two-year-old child recently immigrated and has presented for immunization review. Their immunization record indicates they have received three doses of bivalent oral polio (bOPV) . What polio vaccine(s)  does the child need?

Accepted Answer

A)  None, they are fully vaccinated for polio as recommended
B)  Three doses of inactivated poliovirus (IPV) 
C)  One dose of IPV after four years of age
D)  One dose of trivalent oral polio virus (tOPV) E) None of the above
F) B) and C)

Question 4

The MMR vaccine is not recommended for pregnant women because:

Accepted Answer

A)  Pregnant women do not build adequate immunity to the vaccine.
B)  There is a risk of pregnant women developing measles encephalopathy.
C)  There is a risk of the fetus developing congenital rubella syndrome.
D)  Pregnant women can receive the MMR vaccine.E) None of the above
F) B) and D)

Question 5

Rho(D)  immune globulin (RhoGAM)  is given to:

Accepted Answer

A)  Infants born to women who are Rh positive
B)  Sexual partners of Rh-positive women
C)  Rh-negative women after a birth, miscarriage, or abortion
D)  Rh-negative women at 36 weeks gestationE) All of the above
F) B) and D)

Question 6

Azathioprine has significant adverse drug effects, including:

Accepted Answer

A)  Hypertension
B)  Hirsutism
C)  Risk of cancer
D)  Gingival hyperplasiaE) All of the above
F) B) and C)

Question 7

The reason that two measles, mumps, and rubella (MMR)  vaccines at least a month apart are recommended is:

Accepted Answer

A)  The second dose of MMR "boosts" the immunity built from the first dose.
B)  Two vaccines one month apart is the standard dosing for all live virus vaccines.
C)  If the two MMR vaccine doses are given too closely together there is a greater likelihood of severe localized reaction to the vaccine.
D)  Only 95% of patients are fully immunized for measles after the first vaccine, with 99% having immunity after two doses of MMR.E) None of the above
F) C) and D)

Question 8

True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap)  vaccine include:

Accepted Answer

A)  Fever up to 104oF (40.5o
C)   after previous DTaP vaccine
B)  Family history of seizures after DTaP vaccine
C)  Adolescent pregnancy
D)  Anaphylactic reaction with a previous doseE) B) and C)
F) A) and D)

Question 9

Recombinant influenza vaccine (Flucelvax, Flublok)  may be administered annually to:

Accepted Answer

A)  Patients with an egg allergy
B)  Pregnant adolescent patients
C)  Patients age six weeks or older
D)  Patients with acute febrile illnessE) A) and B)
F) A) and D)

Question 10

Who should receive a third dose of MMR vaccine:

Accepted Answer

A)  Children traveling internationally who have had two doses of MMR
B)  Pregnant women who are exposed to measles
C)  People who have had two doses of MMR and are at risk during a mumps outbreak
D)  No one; a third dose is never recommendedE) A) and B)
F) None of the above

Question 11

Immune globulin serums:

Accepted Answer

A)  Provide active immunity against infectious diseases
B)  Are contraindicated during pregnancy
C)  Are heated to above body temperature to kill most hepatitis, human immunodeficiency virus (HIV) , and other viruses such as parvovirus
D)  Are derived from pooled plasma of adults and contain specific antibodies in proportion to the donor populationE) A) and B)
F) A) and D)

Question 12

The following pediatric patients should receive meningococcal ACWY conjugate vaccine:

Accepted Answer

A)  Infants who are HIV infected
B)  All school-age children
C)  Children who attend daycare
D)  Infants with congenital hearing defectsE) A) and D)
F) None of the above

Question 13

The rotavirus vaccine (RotaTeq, Rotarix) :

Accepted Answer

A)  Is a live vaccine that replicates in the small intestine, providing active immunity against rotavirus
B)  Should not be administered to infants who are or may be immunocompromised
C)  Is not given to an infant who has a febrile illness (temperature greater than 100.5oF) 
D)  All of the aboveE) A) and C)
F) B) and D)

Question 14

Tuberculin purified protein derivative:

Accepted Answer

A)  Is administered to patients who are known tuberculin-positive reactors
B)  May be administered to patients who are on immunosuppressives
C)  Should be administered two to three weeks after an MMR or varicella vaccine
D)  May be administered the same day as the MMR and/or varicella vaccineE) C) and D)
F) A) and C) D

Question 15

Hepatitis B vaccine is contraindicated in patients who:

Accepted Answer

A)  Were born at less than 32 weeks gestation
B)  Are pregnant
C)  Are on hemodialysis
D)  Are allergic to yeastE) B) and D)
F) A) and B) D

Question 16

Pregnant women should receive the Tdap vaccine:

Accepted Answer

A)  In the first trimester
B)  Once every 10 years
C)  In the third trimester of every pregnancy
D)  Tdap is contraindicated in pregnancyE) All of the above
F) A) and B)

Question 17

Hepatitis A virus (HAV)  vaccination is recommended for:

Accepted Answer

A)  All infants traveling internationally, but the dose is not counted
B)  All health-care providers
C)  Members of a household with children adopted from Africa
D)  Immunocompromised patientsE) A) and D)
F) A) and B)

Question 18

Human papillomavirus (HPV)  vaccine (Gardasil) :

Accepted Answer

A)  Is a live virus vaccine that provides immunity to six strains of HPV virus
B)  Has a common adverse effect of syncope within 15 minutes of giving the vaccine
C)  Should not be given to males younger than age 12 years
D)  May be given to pregnant womenE) A) and C)
F) All of the above

Question 19

Attenuated vaccines are also known as:

Accepted Answer

A)  Killed vaccines
B)  Booster vaccines
C)  Inactivated vaccines
D)  Live vaccinesE) C) and D)
F) All of the above

Question 20

Zoster vaccine (Zostavax)  is:

Accepted Answer

A)  A live varicella zoster vaccine from the same strain used to develop the varicella vaccine
B)  Effective in preventing varicella zoster in patients of all ages
C)  Recommended for patients age 40 to 80 who have had chickenpox
D)  Administered at the same time as other live vaccines, as long as they are given the same dayE) B) and C)
F) A) and B)

Exam 16: Drugs Affecting the Immune System

Varicella vaccine may be given to patients who are:

Correct AnswerverifiedShow Answer

Live attenuated influenza vaccine (FluMist) may be administered to:

Correct AnswerverifiedA

A two-year-old child recently immigrated and has presented for immunization review. Their immunization record indicates they have received three doses of bivalent oral polio (bOPV) . What polio vaccine(s) does the child need?

Correct AnswerverifiedShow Answer

The MMR vaccine is not recommended for pregnant women because:

Correct AnswerverifiedShow Answer

Rho(D) immune globulin (RhoGAM) is given to:

Correct AnswerverifiedShow Answer

Azathioprine has significant adverse drug effects, including:

Correct AnswerverifiedShow Answer

The reason that two measles, mumps, and rubella (MMR) vaccines at least a month apart are recommended is:

Correct AnswerverifiedShow Answer

True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap) vaccine include:

Correct AnswerverifiedShow Answer

Recombinant influenza vaccine (Flucelvax, Flublok) may be administered annually to:

Correct AnswerverifiedShow Answer

Who should receive a third dose of MMR vaccine:

Correct AnswerverifiedShow Answer

Immune globulin serums:

Correct AnswerverifiedShow Answer

The following pediatric patients should receive meningococcal ACWY conjugate vaccine:

Correct AnswerverifiedShow Answer

The rotavirus vaccine (RotaTeq, Rotarix) :

Correct AnswerverifiedShow Answer

Tuberculin purified protein derivative:

Correct AnswerverifiedD

Hepatitis B vaccine is contraindicated in patients who:

Correct AnswerverifiedD

Pregnant women should receive the Tdap vaccine:

Correct AnswerverifiedShow Answer

Hepatitis A virus (HAV) vaccination is recommended for:

Correct AnswerverifiedShow Answer

Human papillomavirus (HPV) vaccine (Gardasil) :

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Attenuated vaccines are also known as:

Correct AnswerverifiedShow Answer

Zoster vaccine (Zostavax) is:

Correct AnswerverifiedShow Answer

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Rh_o(D) immune globulin (RhoGAM) is given to:

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D

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D

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