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The Central Dogma of biology can be stated as


A) proteins \rightarrow RNA \rightarrow DNA.
B) RNA \rightarrow DNA \rightarrow proteins.
C) DNA \rightarrow proteins \rightarrow RNA.
D) DNA \rightarrow RNA \rightarrow proteins.

E) A) and B)
F) A) and C)

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The sequence of nucleotides in a DNA molecule is called the ________ code.


A) protein
B) ribosomal
C) translation
D) genetic

E) A) and B)
F) A) and D)

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To begin transcription, RNA polymerase must bind to a segment of DNA called the ____.


A) initiation site
B) primer
C) inducer
D) promoter

E) A) and B)
F) None of the above

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During transcription of mRNA in eukaryotes, some sequences are cut out of the primary transcript and the remaining sequences are joined together.This processing of mRNA is called _________.


A) termination
B) translation
C) splicing
D) capping

E) A) and B)
F) B) and C)

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In eukaryotes, each type of RNA polymerase recognizes a different


A) start codon
B) stop codon
C) promoter
D) release factor

E) B) and C)
F) All of the above

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In eukaryotes, pre-mRNA processing may involve all of the following except


A) removal of exons from the pre-mRNA.
B) addition of a 5' cap.
C) addition of a 3' poly-A tail
D) pre-mRNA splicing by the spliceosome.

E) A) and D)
F) A) and C)

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A bacterial cell has a nonsense mutation that prevents it from producing a functional sigma subunit for RNA polymerase.Inability to synthesize a functional sigma subunit would have the most direct effect on


A) transcription initiation.
B) transcription elongation.
C) transcription termination.
D) translation initiation.

E) All of the above
F) None of the above

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Messenger RNA molecules contain information that is used to synthesize ___________.


A) nucleotides
B) amino acids
C) polypeptides
D) fatty acids

E) B) and D)
F) B) and C)

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During _______, RNA polymerase synthesizes a molecule of RNA using DNA as a template.


A) mRNA splicing
B) translation
C) transcription
D) gene sequencing

E) B) and C)
F) A) and B)

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Both DNA and RNA are made up of building blocks known as


A) nucleotides.
B) nucleic acids.
C) amino acids.
D) genes.

E) A) and D)
F) B) and D)

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In eukaryotes, translation takes place


A) on the plasma membrane.
B) inside the nucleus.
C) on ribosomes.
D) on the nuclear membrane.

E) B) and C)
F) A) and B)

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DNA affects the traits of an organism by providing the instructions for synthesizing _______.


A) proteins
B) nucleotides
C) codons
D) amino acids

E) A) and C)
F) B) and C)

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Although 61 different codons code for amino acids, cells contain fewer than 61 different tRNAs.Why?


A) Because the 5' base on the tRNA anticodon has some flexibility (wobble) ; thus, some tRNA anticodons can pair with more than one mRNA codon.
B) Although 61 different codons code for amino acids, any given cell contains fewer than 61.
C) Because the 5' base on the mRNA codon has some flexibility (wobble) ; thus, some mRNA codons can pair with more than one tRNA anticodon.
D) Because each amino acid is coded for by just one codon.

E) A) and B)
F) A) and C)

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Which molecule combines with proteins to form both the large and small ribosomal subunits?


A) DNA
B) RNA polymerase
C) miRNA
D) rRNA

E) B) and C)
F) A) and D)

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Ribosome movement along the mRNA is called


A) transcription.
B) initiation.
C) replication.
D) translocation.

E) A) and B)
F) B) and C)

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Gene expression involves two phases, ___________ and translation.


A) replication
B) transcription
C) initiation
D) condensation

E) A) and D)
F) C) and D)

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During translation, amino acids are carried to the ribosome by


A) mRNA.
B) tRNA.
C) snRNA.
D) rRNA.

E) A) and D)
F) B) and C)

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The location of translation in prokaryotic cells is


A) in the nucleoid.
B) on ribosomes.
C) on the plasma membrane.
D) on mesosomes.

E) A) and C)
F) A) and D)

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During translation, uncharged tRNA molecules leave the ribosome from the _________ site.


A) E
B) P
C) A
D) termination

E) B) and D)
F) A) and B)

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Which base in an anticodon will pair with the base adenine in a codon?


A) thymine
B) cytosine
C) guanine
D) uracil

E) B) and C)
F) A) and B)

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