Question 1

When comparing the genomes of prokaryotes verse eukaryotes,it can be accurately stated that

Accepted Answer

A)  eukaryotic genomes are larger than prokaryotic genomes.
B)  eukaryotic genomes are smaller than prokaryotic genomes.
C)  the size of the organism determines the size of the genome.
D)  larger and more complex organisms have more genes than smaller,less complex organisms.E) A) and D)
F) C) and D)

Question 2

Microarrays are created by robotically placing DNA on to a microscope slide and probing with

Accepted Answer

A)  RNA from the tissue of interest.
B)  another DNA from the tissue of interest.
C)  SNPs from the tissue of interest.
D)  STSs from the tissue of interest.
E)  clone-by-clone sequencing.F) B) and D)
G) B) and E)

Question 3

The relative location of genes on a chromosome as determined by recombination frequencies is illustrated in a ________ map.

Accepted Answer

A)  DNA
B)  genetic
C)  chromosomal
D)  physicalE) A) and C)
F) None of the above

Question 4

Distances on a genetic map are measured in ________ units.

Accepted Answer

A)  centromere
B)  DNA
C)  dalton
D)  centimorganE) A) and B)
F) B) and D)

Question 5

When comparing the actual number of genes,the organism with the highest number is

Accepted Answer

A)  rice.
B)  human.
C)  fruit fly.
D)  yeast.E) All of the above
F) A) and B)

Question 6

The primary significance of the 1000 Genomes Project is to

Accepted Answer

A)  take into account the variation in human genomes across populations.
B)  account for the inherent error rate of sequencing by including a greater sample size.
C)  identify the 1000 most important genes to human health.
D)  trace human ancestors back 1000 years.E) A) and B)
F) A) and D)

Question 7

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago.However,the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Accepted Answer

A)  linkage disequilibrium.
B)  single nucleotide polymorphisms.
C)  contig.
D)  synteny.
E)  expressed sequence equilibrium.F) A) and B)
G) C) and E)

Question 8

The reason segmental duplications pose a logistical challenge in the proper alignment of DNA sequences is that they

Accepted Answer

A)  are inherently repetitive.
B)  contain large numbers of LINEs,which interfere with sequence annotation.
C)  interfere with BLAST analysis.
D)  are often found in areas of constitutive heterochromatin.E) None of the above
F) A) and B)

Question 9

A defining characteristic of draft sequences is that they have

Accepted Answer

A)  many gaps in regions of highly repetitive DNA.
B)  less than 1 error in 10,000 nucleotides.
C)  been found in various proteomes across the eukaryote life forms.
D)  been produced by alternative splicing.
E)  several problems,the main one being their contiguous DNA fragments.F) D) and E)
G) C) and D)

Question 10

Your research group has recently determined the complete genomic sequence of the organism Examus biologisium.You instruct your group to begin sequence annotation,which involves

Accepted Answer

A)  shotgun cloning.
B)  the alignment of contigs.
C)  the identification of open reading frames.
D)  the construction of a genetic map.E) C) and D)
F) B) and C)

Question 11

You are studying a novel protein.To learn more about it,you performed a screen in yeast to identify proteins that could interact with it.From the screen you got a clone for a second gene.You had the clone sequenced,and you translated the gene sequence on your computer.What is the next logical step to learn more about the function of these two proteins?

Accepted Answer

A)  Run a BLAST search.
B)  Identify the intron/exon organization.
C)  Localize the gene to a specific chromosomal region.
D)  Search the human genome sequence for your clone.E) None of the above
F) A) and B)

Question 12

The majority of DNA in a human can be described as

Accepted Answer

A)  composed of short interspersed elements.
B)  noncoding.
C)  simple sequence repeats.
D)  segmental duplications.
E)  structural.F) B) and E)
G) None of the above

Question 13

To avoid confusion and facilitate ease of data interpretation,researchers working on cloned DNA from the same species use

Accepted Answer

A)  restriction fragment length polymorphisms.
B)  shotgun sequencing.
C)  sequenced-tagged sites.
D)  clone by clone sequencing.
E)  consensus sequencing.F) B) and C)
G) D) and E)

Question 14

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Accepted Answer

A)  shotgun sequencing.
B)  clone-by-clone sequencing.
C)  RFLP sequencing.
D)  consensus sequencing.E) C) and D)
F) A) and D)

Question 15

The best technique for detecting chromosomal abnormalities is

Accepted Answer

A)  EST
B)  FISH
C)  STS
D)  SNPE) None of the above
F) B) and D)

Question 16

Every cell within one organism has the same genome.In what way(s) can these cells differ from each other? (Select all that apply)

Accepted Answer

A)  Number of chromosomes
B)  Ratio of organelles
C)  Proteins produced
D)  Number of genes in the DNA
E)  Surface area of cell membraneF) A) and C)
G) B) and E)

Question 17

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Accepted Answer

A)  single strand polymorphisms.
B)  synteny.
C)  draft sequences.
D)  the proteome.
E)  a contig.F) A) and D)
G) A) and C)

Question 18

The current estimates of the ENCODE project for percent functionality of the human genome based on the ENCODE definition of functionality is ________ the estimate of functionality based on the selected-effect functionality definition.

Accepted Answer

A)  greater than
B)  less than
C)  equal toD) A) and C)
E) All of the above

Question 19

In the United States it is currently legal for a company to patent genes.

Accepted Answer

A) True 
 B)False

Question 20

The inclusive term that describes all of the DNA in the nucleus of a cell is its

Accepted Answer

A)  genome.
B)  chromosome.
C)  gene.
D)  proteome.E) None of the above
F) C) and D)

Exam 18: Genomics

The primary significance of the 1000 Genomes Project is to

Correct Answer
verified

When comparing the genomes of prokaryotes verse eukaryotes,it can be accurately stated that

Correct Answer
verified

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Correct Answer
verified

The best technique for detecting chromosomal abnormalities is

Correct Answer
verified

The relative location of genes on a chromosome as determined by recombination frequencies is illustrated in a ________ map.

Correct Answer
verified

In the United States it is currently legal for a company to patent genes.

Correct Answer
verified

Microarrays are created by robotically placing DNA on to a microscope slide and probing with

Correct Answer
verified

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Correct Answer
verified

The reason segmental duplications pose a logistical challenge in the proper alignment of DNA sequences is that they

Correct Answer
verified

When comparing the actual number of genes,the organism with the highest number is

Correct Answer
verified

A defining characteristic of draft sequences is that they have

Correct Answer
verified

The current estimates of the ENCODE project for percent functionality of the human genome based on the ENCODE definition of functionality is ________ the estimate of functionality based on the selected-effect functionality definition.

Correct Answer
verified

To avoid confusion and facilitate ease of data interpretation,researchers working on cloned DNA from the same species use

Correct Answer
verified

Every cell within one organism has the same genome.In what way(s) can these cells differ from each other? (Select all that apply)

Correct Answer
verified

The majority of DNA in a human can be described as

Correct Answer
verified

Distances on a genetic map are measured in ________ units.

Correct Answer
verified

Your research group has recently determined the complete genomic sequence of the organism Examus biologisium.You instruct your group to begin sequence annotation,which involves

Correct Answer
verified

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago.However,the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Correct Answer
verified

The inclusive term that describes all of the DNA in the nucleus of a cell is its

Correct Answer
verified

Correct Answer
verified

Exam 18: Genomics

The primary significance of the 1000 Genomes Project is to

Correct AnswerverifiedShow Answer

When comparing the genomes of prokaryotes verse eukaryotes,it can be accurately stated that

Correct AnswerverifiedShow Answer

The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called

Correct AnswerverifiedShow Answer

The best technique for detecting chromosomal abnormalities is

Correct AnswerverifiedShow Answer

The relative location of genes on a chromosome as determined by recombination frequencies is illustrated in a ________ map.

Correct AnswerverifiedShow Answer

In the United States it is currently legal for a company to patent genes.

Correct AnswerverifiedShow Answer

Microarrays are created by robotically placing DNA on to a microscope slide and probing with

Correct AnswerverifiedShow Answer

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Correct AnswerverifiedShow Answer

The reason segmental duplications pose a logistical challenge in the proper alignment of DNA sequences is that they

Correct AnswerverifiedShow Answer

When comparing the actual number of genes,the organism with the highest number is

Correct AnswerverifiedShow Answer

A defining characteristic of draft sequences is that they have

Correct AnswerverifiedShow Answer

The current estimates of the ENCODE project for percent functionality of the human genome based on the ENCODE definition of functionality is ________ the estimate of functionality based on the selected-effect functionality definition.

Correct AnswerverifiedShow Answer

To avoid confusion and facilitate ease of data interpretation,researchers working on cloned DNA from the same species use

Correct AnswerverifiedShow Answer

Every cell within one organism has the same genome.In what way(s) can these cells differ from each other? (Select all that apply)

Correct AnswerverifiedShow Answer

The majority of DNA in a human can be described as

Correct AnswerverifiedShow Answer

Distances on a genetic map are measured in ________ units.

Correct AnswerverifiedShow Answer

Your research group has recently determined the complete genomic sequence of the organism Examus biologisium.You instruct your group to begin sequence annotation,which involves

Correct AnswerverifiedShow Answer

Rice and its grain relatives,maize,barley,and wheat,diverged from a common ancestor 50 million years ago.However,the chromosomes of these plants demonstrate extensive conserved arrangements of segments.This phenomenon is called

Correct AnswerverifiedShow Answer

The inclusive term that describes all of the DNA in the nucleus of a cell is its

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified